Tuesday, October 26, 2010

Researchers Snap Most Detailed MRI Images Ever Taken of a .

Researchers Snap Most Detailed MRI Images Ever Taken of a Mammal Brain
The most detailed magnetic resonance images ever obtained of a mammal brainG. Allan Johnson, Duke Center for In Vivo Microscopy

Using an MRI system operating at six times the magnetic field of a conventional clinical scanner, researchers at the Duke Center for In Vivo Microscopy have collected the most detailed magnetic resonance images ever captured of a mammal brain. And while that may sound fairly wonky, the images - which will go into an online atlas open to researchers about the world - will allow researchers to cut and die the brain digitally any way they want, helping researchers across disciplines run virtual experiments on the highly-detailed structure.

A typical MRI scan represents brain tissues in cubic units called voxels that can be thinking of generally as a 3-D pixel in a brain image. But since the new atlas images were taken at a resolution 300,000 times higher than those from a conventional MRI scanner, each voxel is often smaller and more detailed, shrinking from almost 1-by-1-by-3 millimeters to nearly 20 microns per side (a micron being a millionth of a meter).

The images were taken of fixed brain tissue still in the craniums of 8 different mice to belittle the distortions that can happen when the mind is remote or shredded for typical study. But using the tools in the Waxholm Space brain atlas - so named for the Swedish town where the mind for the atlas took shape - the mind can be digitally sliced at any angle, providing researchers with the power to use the brain however they wish without losing resolution.

Using 3 different data acquisition protocols while imaging, the squad was likewise capable to characterize 37 different brain structures, and by mashing up the information from the eight different mice they were likewise capable to produce a framework for an average head and a probabilistic brain. And that`s only the start place for researchers; as new information is acquired it will be registered to the brain atlas site so other researchers can approach it as well, fostering a scheme of information sharing that is far cleaner and more convenient than mailing mouse brains through the post.

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